Orest Georgievich Vereisky was born in the family of artist Georgy Vereisky and Elena Vereyskaya, the daughter of the historian N. I. Kareev. Until 1922 he lived in the village of Anosovo now Novoduginsky district of the Smolensk region.
In 1936–1938, he was a volunteer of the INJSA All-Russian Academy of Arts. It is in Leningrad that the creative formation of Vereisky as an artist takes place. Here his mentor, except his father, was the artist and teacher A. A. Osmyorkin. In 1940, Vereisky moved to live and work in Moscow.
During the Great Patriotic War, he worked in the editorial office of the newspaper Krasnoarmeyskaya Pravda of the 3rd Belorussian Front, where he met and became friends with A. T. Tvardovsky. Full member of the Academy of Arts of the USSR (1983), corresponding member of the Academy of Arts of the USSR (1958).
O. G. Vereisky died on January 2, 1993. He was buried in Moscow at the Kuntsevo Cemetery.
Vereisky is known for his book graphics. He illustrated the works of M. A. Sholokhov, K. G. Paustovsky, A. A. Fadeev, A. N. Rybakov, M. M. Prishvin, I. A. Bunin, E. Hemingway and other writers.
Vereisky actively illustrated the works of A.T. Tvardovsky, including a poem about Vasily Turkin. Known are his illustrations to the book by M. P. Prilezhayeva “The Life of Lenin”.
A prominent place in the work of Verey was taken by easel graphics. He owns various series of drawings, watercolors, autolithographs, created as a result of his travels around Czechoslovakia, Syria, Lebanon, Egypt (all in 1955), Finland (1957), Iceland (1958), USA (1960 and 1963 ).