was the main assistant to Niccolò Pisano in the work on the marble pulpit of the cathedral in Siena (1265-1268). Soon he began to work independently in the genre of funerary sculpture.
In 1266-1267, di Cambio was in Rome, on the Capitol there is a statue of King Charles I of Anjou by his work.
Around 1282, he completed the monument to Cardinal de Brauil in the church of San Domenico in Orvieto. The statue of the Madonna on the tomb of Cardinal di Cambio was created from a converted statue of the Roman goddess of Fertility. It is possible that the project of the cathedral belongs to di Cambio. In Rome, di Cambio became acquainted with the cosmatesco, a decorative style typical of this city. The influence of Cosmatesco can be seen in the works of the sculptor for the basilicas of San Paolo fuori le Mura (1285) and Santa Cecilia in Trastevere (1293). At the same time, he created nativity scenes for Santa Maria Maggiore and Santa Maria in Aracheli, a monument to Pope Boniface VIII (1300) and a bronze statue of St. Peter in St. Peter's Basilica.
From 1294 to 1295 he worked in Florence, mainly as an architect. According to Giorgio Vasari, di Cambio was responsible for the construction of the city's cathedral, for which he also executed the statues that adorned the lower part of the façade (lost in 1589). The surviving sculptures are currently in the cathedral's museum. He is credited with the beginning of the construction of the Palazzo Vecchio. It is also possible that di Cambio designed the Church of Santa Croce in Florence. Vasari also credited him with creating a plan for the new city of San Giovanni Valdarno. One of the master's best works is the Maggiore fountain in the square in Perugia (1278), created jointly with Niccolò and Giovanni Pisano. The fountain was decorated with numerous statues and reliefs. It was forbidden to water animals from this fountain and to collect water in dirty dishes. The figures made for the fountain have been preserved in fragments.
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